People taking methotrexate long term need ongoing testing to monitor their blood counts and liver function. Acitretin and other retinoids are pills used to reduce the production of skin cells.

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Pineapple has an anti-inflammatory enzyme called bromelain. “Smoking is toxic to every organ system and is especially toxic to the skin.” “There have been reports that coffee increases the risk of psoriasis and that coffee helps quell psoriasis,” he said. However, this study found no risk or benefit from coffee, Qureshi added. In the study, those who drank the most coffee also drank the most alcohol and smoked, he said.

Oral fish oil therapy used in combination with UVB therapy might reduce the amount of affected skin. Applying fish oil to the affected skin and covering it with a dressing for six hours a day for four weeks might improve scaling.

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• In rare cases, behavioral modification like weight loss or smoking cessation may be associated with improvements or complete clearing.
• For the majority of people, psoriasis doesn’t go away on its own.
• In genetically predisposed people, an environmental factor acts as a trigger to unmask psoriasis.
• This is a challenge for anyone, but it can be even more challenging if you have psoriasis.
• Psoriasis plaques that occur on weakened skin can lead to pain and bleeding.

Thioguanine and hydroxyurea are medications that can be used when other drugs can’t be given. Talk with your doctor about possible side effects of these drugs. Usually administered weekly as a single oral dose, methotrexate decreases the production of skin cells and suppresses inflammation. It’s less effective than adalimumab and infliximab . It might cause upset stomach, loss of appetite and fatigue.

Calcineurin inhibitors are not recommended when you’re pregnant or breast-feeding or if you intend to become pregnant. This drug is also not intended for long-term use because of a potential increased risk of skin cancer and lymphoma. Synthetic forms of vitamin D, such as calcipotriene and calcitriol slow skin cell growth. This weight loss type of drug may be used alone or with topical corticosteroids.

Side effects might include dry skin and muscle soreness. These drugs are not recommended when you’re pregnant or breast-feeding or if you intend to become pregnant. If you have a few small, persistent psoriasis patches, your doctor might suggest an injection of triamcinolone right into the lesions. Coal tar treatment isn’t recommended for women who are pregnant or breast-feeding.

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Calcitriol may cause less irritation in sensitive areas. Calcipotriene and calcitriol are usually more expensive than topical corticosteroids. Quality CareFind out why Mayo Clinic is the right place for your health care. Fruits have antioxidants, fiber, and other vitamins that fight inflammation. Berries, cherries, and apples have antioxidants called polyphenols, while oranges and melons are high in vitamin C.